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Mitragyna Speciosa: Taking the American Counterculture by Storm

Mitragyna Speciosa: Taking the American Counterculture by Storm

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August 15, 2017 By John Reed 1 Comment

Mitragyna Speciosa, A.K.A. Kratom, has almost become a staple in the American counterculture. Walk into any head shop, smoke shop, or locally owned convenience store and you are sure to find hidden behind the counter at least the Maeng Da strain, if you are lucky there will be a couple of others to choose from. Kratom was not widely known until the Food and Drug Administration decided to place kratom on the radar back in October 2016. The DEA blindsided consumers in August with a sudden announcement that it would make two compounds in kratom – mitragynine and 7-hydroxymitragynine – Schedule I substances, effectively banning the plant with as little as 30 days’ notice. By doing so, the FDA only hindered their hopes of banning the beneficial herb due to an overwhelming outcry by the kratom community. 1

Never before has the FDA seen a public campaign of this nature. “Based on the response we’ve gotten over the last month or so, we believe it’s the prudent and reasonable action to take,” DEA spokesman Russ Baer says. “We want to make sure this is a transparent process. We want to have an open dialog with the public.”2 During the public comment period, well over 2,000 kratom advocates, who were greatly opposed to the ban called the FDA to share their concerns and personal success stories in hopes of overturning their decision to ban the supplement.  “That was eye-opening for me personally,” DEA spokesperson Melvin Patterson said to the Washington Post. “I want the kratom community to know that the DEA does hear them. Our goal is to make sure this is available to all of them.”3 Another spokesman for the FDA, Russ Baer, went on to say “They have claimed individually that kratom has given them medical value,” Baer says, “that it has medical utility ranging from migraine headaches to chronic pain, to Crohn’s disease, to anxiety, depression, opioid withdrawal – these are all conditions that medicines usually try to alleviate.”2 Even the President took notice when upset advocates flooded the White House with petitions urging Donald Trump to second guess the FDA’s hasty actions.4 Lawmakers throughout the United States also began signing legislature in hopes of gaining both public popularity and also voicing their opinions as kratom advocates, and users as well.

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Since the initial threat of a ban, Kratom sales have boosted throughout America both online and in the storefront. In August, when the threat of a ban loomed heavily on the kratom community, online stores experienced an overnight boom in sales leaving most vendors out of stock until things smoothed over. Many advocates, out of fear of losing access to the herb, began seeking sources outside the United States. Vendors in Indonesia began flooding Facebook groups in attempts to gain access to the Kratom community. Many offer the best strains, kilograms for under $70, and guaranteed shipment through customs. Canadian farms also became another source for many Kratom connoisseurs to purchase through. This left many buyers in outrage as their product was confiscated in route by customs, or they sent money via PayPal only to never hear from the seller again and be out large sums of money.

When researching Kratom use, or rise thereof, in the United States, I found little information on the exact number of users. In fact, since studies in general have rarely been conducted a search through Google only turned up minimal information. One thread on Reddit had this to say on use of kratom in America today, Reason I ask is that over the last couple of weeks I’ve seen a variety of numbers from articles/posts stating hundreds to thousands. It’s hard to get a grasp on the size of the potential constituency unless we have an idea. From the DEA’s own intent letter, they mention 55,000kg being encountered by Law Enforcement in two years (2014-2016), or close to 12 million doses (their estimation). That number of just the encountered amount really seems high for hundreds or thousands of people. Makes me wonder if the Kratom community is much bigger than we even know.

I think it’s a point worth investigating. If anyone has any ideas, I’d love to hear them. This question could be helped by any vendors that have a raw count too. This information might be useful to the AKA.”5

Regardless of the number of users, it is safe to say that Mitragyna Speciosa has taken American counterculture by storm! Whether it is used to wean off narcotics, or to eliminate pain in chronic pain patients, or one of the other many beneficial reasons to take kratom, the fact cannot be denied that Americans love their kratom! And by the looks of it, it is luckily not leaving the scene anytime soon.

Filed Under: Kratom (Mitragyna speciosa) Tagged With: Kratom, Kratom sales, kratom use, Mitragyna speciosa

Mitragyna Speciosa: Could This Be the Answer to America’s Opioid Epidemic?

Mitragyna Speciosa: Could This Be the Answer to America’s Opioid Epidemic?

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June 27, 2017 By John Reed 1 Comment

As the pharmaceutical companies continue to push narcotics onto Americans, the rate for addiction and death has almost tripled over the last decade. According to the World Drug Report in 2012, “It is estimated that between 26.4 million and 36 million people abuse opioids worldwide,1 with an estimated 2.1 million people in the United States suffering from substance abuse disorders related to prescription opioid pain relievers in 2012 and an estimated 467,000 addicted to heroin.”2 According to the National Center for Health Statistics, the number of overdose deaths involving opioids rose from 28,647 in 2014 to 33,091 in 2015.3

  • Heroin overdose deaths rose from 10,574 in 2014 to 12,990 in 2015, an increase of 23 percent.
  • Overdose deaths involving synthetic opioids other than methadone rose from 5,544 in 2014 to 9,580 in 2015, an increase of 73 percent. This category of opioids is dominated by fentanyl-related overdoses, and recent research indicates the fentanyl involved in these deaths is illicitly manufactured, not from medications containing fentanyl.
  • Taken together, 19,885 Americans lost their lives in 2015 to deaths involving primarily illicit opioids: heroin, synthetic opioids other than methadone (e.g., fentanyl), or a mixture of the two.
  • Overdose deaths involving prescription opioids, excluding the category predominated by illicit fentanyl, rose only slightly from 16,941 in 2014 to 17,536 in 2015, a 4% increase.
  • NOTE: A portion of the overdose deaths involved both illicit opioids and prescription opioids.3 

   

       Fig.1

The total number of opioid pain relievers prescribed in the United States has skyrocketed in the past 25 years. The number of prescriptions for opioids (like hydrocodone and oxycodone products) have escalated from around 76 million in 1991 to nearly 207 million in 2013, with the United States their biggest consumer globally, accounting for almost 100 percent of the world total for hydrocodone (e.g., Vicodin) and 81 percent for oxycodone (e.g., Percocet).4

Recently, the DEA and FDA began working together to crack down on the amount of opiates distributed in America by physicians and pharmaceutical companies; such as hydrocodone, oxycontin and morphine. “Fourteen billion opioid pills are now dispensed annually in the United States – enough for every adult American to have a bottle of pills. Certainly, the pharmaceutical industry is at fault for decades of misleading information about their products and the medical community bears responsibility for its role in over-prescribing these dangerous and addictive drugs, but we remain deeply troubled by the sheer volume of opioids available – volumes that are approved by DEA.”5

Kratom Is a Surprising Answer to This Terrifying Dilemma

Kratom is neither a drug nor an opiate. It is a deciduous tree that grows natively in Southeast Asia and has been used for its healing properties for centuries. The leaves of the plant contain dozens of alkaloids that can produce both stimulation and sedation as well as euphoria in those that ingest it. 7-hydroxymitragynine and Mitragynine are the most active alkaloids contained within the herb and are believed to be responsible for most of the effects that it produces.  Mitragynine (the most plentiful alkaloid) is an opioid agonist, meaning that it is drawn toward the opioid receptors in the brain. In the brain of an addict, those opiate receptors begin to ‘cry out’, so to speak, for that drug. Kratom’s unique alkaloid 7-hydroxymitragynine bind to those needy receptors and ease the withdrawal symptoms by tricking the brain into thinking it has found its fix.

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Side effects of Maend Da

A dose of Kratom can help to relieve the unpleasant side effects of the withdrawal by attaching its alkaloids to the delta-opioid receptors in the brain.  Although opiate drugs bind to the mu-opioid receptors, the mitragynine’s unique ability to attach to the delta receptors can relieve withdrawal symptoms without the risk of further dependency, thus alleviating these common withdrawal symptoms:

  • Anxiety
  • Muscle aches
  • Increased tearing
  • Insomnia
  • Runny nose
  • Sweating
  • Yawning
  • Abdominal cramping
  • Diarrhea
  • Dilated pupils
  • Goose bumps
  • Nausea
  • Vomiting
  • Agitation

The effects can be felt in as little as ten minutes and can last six hours or more, depending on the type of Kratom and how much was taken.  Kratom will not produce extremely strong euphoric feelings like opiates do, but it can soothe an opiate addiction successfully, and is a much safer and healthier alternative to methadone or suboxone.

All Kratom types affect the opioid receptors in some way and can provide relief from withdrawal symptoms.  The most popular choice for addicts are the red vein strains due to their sedating and strong pain-relieving qualities. At high doses, almost any type of Kratom will provide sedation, however the red strains are generally better suited for withdrawal symptoms.  White vein Thai, Red vein Borneo, Red vein Thai and Red vein Malay are all popular strains for this purpose.7

When using Kratom for opiate withdrawals, it is important to remember to monitor your dosing closely. Using Kratom for this purpose will require a higher dose than someone who was just using it to enhance their mood or treat mild pain.  While Kratom is not addictive, it can be habit forming.  In larger quantities, kratom can cause ill effects; such as nausea, vomiting, headaches and dizziness. Do not use more than recommended. Below is the general Kratom dosing guide.  Most Kratom users reach their desired effects in the mild and moderate ranges, however a heavy opiate user may need to use doses in the strong and very strong range to ease their withdrawals.  This, of course, is determined by the quantity and type of narcotics the person is used to consuming, their body composition, the strain of Kratom and other unique variables.  It is always safest to use the smallest amount of Kratom to ease your symptoms.  As time passes, you can lower your dose and use Kratom more sporadically.7

Strength Dose Effect
     
Threshold
1-3 grams
subtle
Mild 2-4 grams stimulant-like
Moderate 3-6 grams stimulant or sedative-like
Strong 6-10 grams more sedative/euphoric
Very Strong 8-15 grams very sedative/euphoric

The above table represents an ‘average’ amongst Kratom users and should only be used as a guide. Results vary from person to person and from plant to plant based on many factors8

[1]https://www.drugabuse.gov/about-nida/legislative-activities/testimony-to-congress/2016/americas-addiction-to-opiods-heroin-prescription-drug-abuse.html

[2]UNODC, World Drug Report 2012. http://www.unodc.org/unodc/en/data-and-analysis/WdR-2012.htm[3] https://obamawhitehouse.archives.gov/the-press-office/2016/12/08/continued-rise-opioid-overdose-deaths-2015-shows-urgent-need-treatment

[4]International Narcotics Control Board Report 2008.United Nations Pubns. 2009. Pg.20

[5]https://www.painnewsnetwork.org/stories/2016/10/4/dea-cutting-opioid-supply-in-2017

[6] https://medlineplus.gov/ency/article/000949.htm

[7] http://kratomrevealed.com/kratom-for-opiate-withdrawal-definitive-guide/

Other articles that may interest you

  • A Beginner’s Guide to Kratom Usage
  • Kratom Maeng Da: An Extended research of user’s experiences

Filed Under: Kratom (Mitragyna speciosa) Tagged With: Kratom, kratom use, Mitragyna speciosa

The Kratom Bible – A Complete Guide to Kratom

The Kratom Bible – A Complete Guide to Kratom

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June 11, 2014 By John Reed 1 Comment

Traditional Kratom Use


kratom useKratom
has been used in Southeast Asia for thousands of years and leaves are still chewed today by about 70% of Thai men. Kratom use in Thailand and Malaysia is considered equivalent to drinking coffee. It is valued by workers for it’s ability to help them ward off fatigue during long, strenuous work days. Traditionally, the most common way to use Kratom is by chewing the fresh leaves, which highlights the plants stimulating effects. Dried leaves are also brewed into tea. Tea is actually more psychoactive than fresh leaves, so it tends to produce sedative, rather than stimulating, effects.

Traditional Kratom use is almost exclusively associated with male workers. This is due to the effectiveness of Kratom at increasing motivation and capacity to work effectively. Laborers in rural areas of Southeast Asia typically have extremely physical jobs such as rubber tapping, which require incredible endurance. Kratom is seen as a safe and effective aid to completing each day’s work.

Medicinal Kratom Use

Kratom users value the plant for several therapeutic purposes. It is not currently employed by medical professionals in North America, but many health professionals are interested in researching it to further investigate therapeutic claims.

One of the major benefits claimed by users is relief from pain. Many people use Kratom to successfully treat moderate pain, as a safe alternative to opiates and other prescription painkillers. For some people it constitutes an effective remedy for severe pain.

Related to it’s role as a painkiller, Kratom has been shown to be effective for treating addiction to opiates. It also helps ease the symptoms of opiate withdrawal and acts as an opiate substitute to help addicts get through strong cravings that may lead to relapse in the early stages of recovery.

Other potential uses for Kratom that are of interest include treatment of diabetes and high blood pressure, and use as an antidepressant. Studies into these potential uses are still preliminary, but early findings and anecdotal evidence hold promise that it may provide relief for these conditions and possibly others.

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Kratom in the Western World

While Kratom is still relatively unknown in the Western world, it has found a dedicated following in North America. Western Kratom users most often consume the drug in a tea, as capsules, or in an extract. Many people use Kratom purely for recreational purposes, but an equal number of people use it to help manage pain or ease opiate withdrawal symptoms.

Recreational users vary dosage based on the effects they are seeking. Many people enjoy the stimulant effects that come from a How to use Kratomlower dose. At a low dose, its use will improve performance of monotonous work, and makes the user more talkative and social. These effects are accompanied by an increase in alertness, and possibly an increase in libido. At higher doses, Kratom begins to mimic the effects of opiates. Users experience a euphoric feeling of sedation lasting about six hours, with an “after glow” effect the next day. As with opiates, the side-effects at high doses can include sweating, itching, constricted pupils and sometimes nausea.

At very high doses, the opiate-like effects of Kratom can become very strong and unsuitable for most recreational users.

Kratom Safety

Kratom is generally considered safe for use by otherwise healthy individuals. In Thailand, where the plant has been used by a large portion of the population for thousands of years, most medical professionals and government officials recognize that Kratom has a long history of use without causing any significant health or societal issues. While Kratom has a long history of safe use, there is the potential for many unwanted and possibly dangerous side-effects when especially large doses are consumed.

An important part of taking Kratom safely is using it in a safe environment. The sedative effects of Kratom make it unsafe to operate vehicles or machinery, or engage in tasks that require alertness and coordination. Kratom has stimulating effects at low doses, but dosage depends highly on the individual and it’s possible to take too much Kratom to engage in certain activities safely.

Another concern when taking Kratom is the potential for abuse, however, when taken occasionally it is not habit forming. But when consistently used on a daily basis, it will create mild physical dependence. Physical withdrawal from Kratom is not nearly as difficult as withdrawal from alcohol or opiates, but the potential for addiction exists and should be considered before using Kratom multiple days in a row.

Kratom Legality

Kratom is legal throughout North America and Europe. It is unlikely that Kratom will become illegal anywhere in North America or Europe in the near future, but the plant is on the United State Drug Enforcement Agency’s “Drug and Chemical of Concern” list. Kratom is illegal in Australia and Thailand. The Thai Office of the Narcotics Control Board (ONCB) recognizes that the initial criminalization of Kratom was done solely for economic reasons, as Kratom competed with the opiate trade, and the ONCB is in the process of decriminalizing Kratom, because they recognize the plant’s cultural significance to the Thai people.

Filed Under: Kratom (Mitragyna speciosa) Tagged With: Kratom, Kratom Extract, kratom legality, Kratom Thai Powder, kratom use, Mitragyna speciosa

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